Frequently Asked
Common questions about 2-Amino-5-iodobenzoic acid
What is 2-Amino-5-iodobenzoic acid used for?
2-Amino-5-iodobenzoic acid is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and sonogashira and heck coupling with the lowest activation barrier among aryl halides.
Where can I buy 2-Amino-5-iodobenzoic acid in the USA?
ChemContract Research is a trusted USA-based supplier of 2-Amino-5-iodobenzoic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-Amino-5-iodobenzoic acid?
ChemContract Research supplies 2-Amino-5-iodobenzoic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-Amino-5-iodobenzoic acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-Amino-5-iodobenzoic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reactions can I run with 2-Amino-5-iodobenzoic acid?
As a iodinated compound, 2-Amino-5-iodobenzoic acid is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
What reactions can I perform with the amine group in 2-Amino-5-iodobenzoic acid?
The amine functionality in 2-Amino-5-iodobenzoic acid enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
How should I store 2-Amino-5-iodobenzoic acid?
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-Amino-5-iodobenzoic acid?
The CAS Registry Number for 2-Amino-5-iodobenzoic acid is 5326-47-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
