Frequently Asked
Common questions about 2-amino-5-fluoropyridine-3-carboxylic acid
What is 2-amino-5-fluoropyridine-3-carboxylic acid used for?
2-amino-5-fluoropyridine-3-carboxylic acid is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and metabolic blocking strategy — fluorine substitution to improve drug half-life.
Where can I buy 2-amino-5-fluoropyridine-3-carboxylic acid in the USA?
ChemContract Research is a trusted USA-based supplier of 2-amino-5-fluoropyridine-3-carboxylic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-amino-5-fluoropyridine-3-carboxylic acid?
ChemContract Research supplies 2-amino-5-fluoropyridine-3-carboxylic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-amino-5-fluoropyridine-3-carboxylic acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-amino-5-fluoropyridine-3-carboxylic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
Why is fluorine important in 2-amino-5-fluoropyridine-3-carboxylic acid?
The fluorine atom(s) in 2-amino-5-fluoropyridine-3-carboxylic acid confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 2-amino-5-fluoropyridine-3-carboxylic acid valuable in pharmaceutical development.
What drug discovery applications use 2-amino-5-fluoropyridine-3-carboxylic acid?
The Pyridine ring system(s) in 2-amino-5-fluoropyridine-3-carboxylic acid is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
How should I store 2-amino-5-fluoropyridine-3-carboxylic acid?
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-amino-5-fluoropyridine-3-carboxylic acid?
The CAS Registry Number for 2-amino-5-fluoropyridine-3-carboxylic acid is 1196154-03-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
