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2-AMINO-5-BROMOBENZONITRILE

CAS 39263-32-6 · Amine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

2-AMINO-5-BROMOBENZONITRILE

Halogenated PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalResearch
CAS Number 39263-32-6
Category Amine · Brominated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2-AMINO-5-BROMOBENZONITRILE

2-AMINO-5-BROMOBENZONITRILE (CAS Number: 39263-32-6) is an amine-functionalized compound with nucleophilic nitrogen reactivity. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. The nitrile group is a bioisostere for both carboxylic acids and amides, and has emerged as a covalent warhead in next-generation kinase inhibitors like saxagliptin and neratinib.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and grignard reagent preparation via magnesium insertion into c–br bond. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 2-AMINO-5-BROMOBENZONITRILE for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Amine (–NH₂/–NHR)Nitrile (–C≡N)Bromine (C–Br)

Amine Applications & Target Industries

How 2-AMINO-5-BROMOBENZONITRILE is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

Grignard reagent preparation via magnesium insertion into C–Br bond

03

Hydrolysis to carboxylic acids or amides under controlled conditions

04

Reductive amination with aldehydes and ketones for secondary amine synthesis

05

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

06

Click chemistry precursor for tetrazole formation (azide–nitrile cycloaddition)

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalResearch

2-AMINO-5-BROMOBENZONITRILE Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2-AMINO-5-BROMOBENZONITRILE
Type Amine
Category Amine · Brominated Compound
Purity ≥95% (custom grades available)
Complexity Moderate (3 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Some nitriles may release HCN upon decomposition. Handle in a well-ventilated fume hood with a cyanide antidote kit accessible.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store in a cool, dry, well-ventilated area. Keep tightly sealed and away from acids and strong bases.

Why Buy 2-AMINO-5-BROMOBENZONITRILE From ChemContract?

Quality Assured

Every batch of 2-AMINO-5-BROMOBENZONITRILE is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2-AMINO-5-BROMOBENZONITRILE? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2-AMINO-5-BROMOBENZONITRILE

What is 2-AMINO-5-BROMOBENZONITRILE used for? +

2-AMINO-5-BROMOBENZONITRILE is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and grignard reagent preparation via magnesium insertion into c–br bond.

Where can I buy 2-AMINO-5-BROMOBENZONITRILE in the USA? +

ChemContract Research is a trusted USA-based supplier of 2-AMINO-5-BROMOBENZONITRILE. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2-AMINO-5-BROMOBENZONITRILE? +

ChemContract Research supplies 2-AMINO-5-BROMOBENZONITRILE in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2-AMINO-5-BROMOBENZONITRILE in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2-AMINO-5-BROMOBENZONITRILE from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 2-AMINO-5-BROMOBENZONITRILE? +

As a brominated compound, 2-AMINO-5-BROMOBENZONITRILE is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

What reactions can I perform with the amine group in 2-AMINO-5-BROMOBENZONITRILE? +

The amine functionality in 2-AMINO-5-BROMOBENZONITRILE enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

How should I store 2-AMINO-5-BROMOBENZONITRILE? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store in a cool, dry, well-ventilated area. Keep tightly sealed and away from acids and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2-AMINO-5-BROMOBENZONITRILE? +

The CAS Registry Number for 2-AMINO-5-BROMOBENZONITRILE is 39263-32-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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