Frequently Asked
Common questions about 2-Amino-4-iodobenzoicacid methyl ester
What is 2-Amino-4-iodobenzoicacid methyl ester used for?
2-Amino-4-iodobenzoicacid methyl ester is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and sonogashira and heck coupling with the lowest activation barrier among aryl halides.
Where can I buy 2-Amino-4-iodobenzoicacid methyl ester in the USA?
ChemContract Research is a trusted USA-based supplier of 2-Amino-4-iodobenzoicacid methyl ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-Amino-4-iodobenzoicacid methyl ester?
ChemContract Research supplies 2-Amino-4-iodobenzoicacid methyl ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-Amino-4-iodobenzoicacid methyl ester in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-Amino-4-iodobenzoicacid methyl ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reactions can I run with 2-Amino-4-iodobenzoicacid methyl ester?
As a iodinated compound, 2-Amino-4-iodobenzoicacid methyl ester is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
What reactions can I perform with the amine group in 2-Amino-4-iodobenzoicacid methyl ester?
The amine functionality in 2-Amino-4-iodobenzoicacid methyl ester enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
How should I store 2-Amino-4-iodobenzoicacid methyl ester?
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
