Frequently Asked
Common questions about 2-(1-Piperazinyl)-benzoic acid ethyl ester
What is 2-(1-Piperazinyl)-benzoic acid ethyl ester used for?
2-(1-Piperazinyl)-benzoic acid ethyl ester is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif used primarily in the pharmaceutical and cns therapeutics industries. Key applications include solubility enhancer via piperazine salt formation in drug formulation and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.
Where can I buy 2-(1-Piperazinyl)-benzoic acid ethyl ester in the USA?
ChemContract Research is a trusted USA-based supplier of 2-(1-Piperazinyl)-benzoic acid ethyl ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-(1-Piperazinyl)-benzoic acid ethyl ester?
ChemContract Research supplies 2-(1-Piperazinyl)-benzoic acid ethyl ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-(1-Piperazinyl)-benzoic acid ethyl ester in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-(1-Piperazinyl)-benzoic acid ethyl ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reagents work best with 2-(1-Piperazinyl)-benzoic acid ethyl ester?
For amide bond formation from the carboxylic acid in 2-(1-Piperazinyl)-benzoic acid ethyl ester, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
What drug discovery applications use 2-(1-Piperazinyl)-benzoic acid ethyl ester?
The Piperazine ring system(s) in 2-(1-Piperazinyl)-benzoic acid ethyl ester is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
How should I store 2-(1-Piperazinyl)-benzoic acid ethyl ester?
Store at room temperature in a tightly sealed container away from acids. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-(1-Piperazinyl)-benzoic acid ethyl ester?
The CAS Registry Number for 2-(1-Piperazinyl)-benzoic acid ethyl ester is 180417-98-5. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
