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1H-Indol-4-amine

CAS 5192-23-4 · Amine · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

1H-Indol-4-amine

Amines PharmaceuticalPolymerAgrochemicalCatalysisMedicinal ChemistryAnalytical Chemistry
CAS Number 5192-23-4
Category Amine · Stereodefined Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 1H-Indol-4-amine

1H-Indol-4-amine (CAS Number: 5192-23-4) is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Indole ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and enantiopure building block for single-enantiomer drug development. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 1H-Indol-4-amine for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Indole
Functional Groups: Amine (–NH₂/–NHR)
Stereochemistry: Defined Configuration

Amine Applications & Target Industries

How 1H-Indol-4-amine is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

Enantiopure building block for single-enantiomer drug development

03

Reductive amination with aldehydes and ketones for secondary amine synthesis

04

Chiral resolution standard or chiral HPLC reference compound

05

Salt formation to improve drug solubility and bioavailability

06

Asymmetric synthesis substrate with defined stereochemistry

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisMedicinal ChemistryAnalytical Chemistry

1H-Indol-4-amine Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 1H-Indol-4-amine
Type Amine
Category Amine · Stereodefined Compound
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (1 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy 1H-Indol-4-amine From ChemContract?

Quality Assured

Every batch of 1H-Indol-4-amine is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 1H-Indol-4-amine? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 1H-Indol-4-amine

What is 1H-Indol-4-amine used for? +

1H-Indol-4-amine is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and enantiopure building block for single-enantiomer drug development.

Where can I buy 1H-Indol-4-amine in the USA? +

ChemContract Research is a trusted USA-based supplier of 1H-Indol-4-amine. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 1H-Indol-4-amine? +

ChemContract Research supplies 1H-Indol-4-amine in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 1H-Indol-4-amine in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 1H-Indol-4-amine from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of 1H-Indol-4-amine? +

ChemContract Research supplies 1H-Indol-4-amine with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

What reactions can I perform with the amine group in 1H-Indol-4-amine? +

The amine functionality in 1H-Indol-4-amine enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

How should I store 1H-Indol-4-amine? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 1H-Indol-4-amine? +

The CAS Registry Number for 1H-Indol-4-amine is 5192-23-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

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