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1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci

CAS 69785-28-0 · Ketone · 4 functional traits · cGMP compliant · Ships from USA in 2-3 days

Ketone

1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci

Heterocycles PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis
CAS Number 69785-28-0
Category Ketone · Heterocyclic Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci

1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci (CAS Number: 69785-28-0) is a ketone-containing compound with a carbonyl center flanked by carbon substituents featuring Pyrimidine, Benzene ring systems with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Ketones serve as strategic intermediates in retrosynthetic planning — their carbonyl can be disconnected in multiple directions, providing flexible synthetic access to complex targets. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility.

Primary applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: PyrimidineBenzene
Functional Groups: Hydroxyl (–OH)
Stereochemistry: Defined Configuration

Ketone Applications & Target Industries

How 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci is used across pharmaceutical and fine chemical sectors

01

Asymmetric reduction to chiral alcohols using CBS or Noyori catalysts

02

Core scaffold in kinase inhibitor design for oncology therapeutics

03

Mitsunobu reaction substrate for stereospecific inversion at chiral centers

04

Enantiopure building block for single-enantiomer drug development

05

Grignard and organolithium additions for tertiary alcohol synthesis

06

GPCR modulator development for CNS and cardiovascular indications

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis

1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci Specifications

Detailed specifications for this ketone, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci
Type Ketone
Category Ketone · Heterocyclic Compound
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (1 functional groups, 2 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Ketones

Handling Guidelines

Handle with standard laboratory precautions. Some ketones are flammable. Use adequate ventilation and wear safety glasses and gloves. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci From ChemContract?

Quality Assured

Every batch of 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci

What is 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci used for? +

1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci is a ketone-containing compound with a carbonyl center flanked by carbon substituents used primarily in the pharmaceutical and fine chemical industries. Key applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and core scaffold in kinase inhibitor design for oncology therapeutics.

Where can I buy 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci in the USA? +

ChemContract Research is a trusted USA-based supplier of 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? +

ChemContract Research supplies 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? +

ChemContract Research supplies 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

What drug discovery applications use 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? +

The Pyrimidine ring system(s) in 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? +

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci? +

The CAS Registry Number for 1,2,5,6-Tetrahydro-6-(2-hydroxyphenyl)-4-methyl-2-oxo-5-pyrimidinecarboxylic aci is 69785-28-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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