Brominated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
4-Bromo-2,6-dimethyl-iodobenzene is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling featuring a Benzene ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.
Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and sonogashira and heck coupling with the lowest activation barrier among aryl halides. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 4-Bromo-2,6-dimethyl-iodobenzene for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 4-Bromo-2,6-dimethyl-iodobenzene is used across pharmaceutical and fine chemical sectors
Grignard reagent preparation via magnesium insertion into C–Br bond
Sonogashira and Heck coupling with the lowest activation barrier among aryl halides
Enantiopure building block for single-enantiomer drug development
Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling
Radioiodination precursor for SPECT and PET diagnostic imaging
Chiral resolution standard or chiral HPLC reference compound
Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.
Aryl and alkyl bromides like 4-Bromo-2,6-dimethyl-iodobenzene are optimized for cross-coupling. We verify halide integrity and provide Pd-catalyst compatibility data on request.
Every batch of 4-Bromo-2,6-dimethyl-iodobenzene is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 4-Bromo-2,6-dimethyl-iodobenzene? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 4-Bromo-2,6-dimethyl-iodobenzene
4-Bromo-2,6-dimethyl-iodobenzene is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and sonogashira and heck coupling with the lowest activation barrier among aryl halides.
ChemContract Research is a trusted USA-based supplier of 4-Bromo-2,6-dimethyl-iodobenzene. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 4-Bromo-2,6-dimethyl-iodobenzene in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 4-Bromo-2,6-dimethyl-iodobenzene from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
ChemContract Research supplies 4-Bromo-2,6-dimethyl-iodobenzene with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
As a brominated compound, 4-Bromo-2,6-dimethyl-iodobenzene is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
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