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2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-

CAS 118289-55-7 · Chlorinated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Chlorinated Compound

2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-

Halogenated PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingMedicinal ChemistryAnalytical Chemistry
CAS Number 118289-55-7
Category Chlorinated Compound · Stereodefined Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
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About 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-

2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- (CAS Number: 118289-55-7) is a chloro-substituted intermediate widely used in nucleophilic displacement reactions featuring a Indole ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.

Primary applications include nucleophilic aromatic substitution (snar) for ether and amine formation and enantiopure building block for single-enantiomer drug development. This compound serves researchers and manufacturers across the pharmaceutical, agrochemical, fine chemical sectors. Whether you require 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Indole
Functional Groups: Chlorine (C–Cl)
Stereochemistry: Defined Configuration

Chlorinated Compound Applications & Target Industries

How 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- is used across pharmaceutical and agrochemical sectors

01

Nucleophilic aromatic substitution (SNAr) for ether and amine formation

02

Enantiopure building block for single-enantiomer drug development

03

Grignard reagent precursor for C–C bond construction

04

Chiral resolution standard or chiral HPLC reference compound

05

Acyl chloride reactivity for amide and ester formation

06

Asymmetric synthesis substrate with defined stereochemistry

Target Industries: PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingMedicinal ChemistryAnalytical Chemistry

2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- Specifications

Detailed specifications for this chlorinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-
Type Chlorinated Compound
Category Chlorinated Compound · Stereodefined Compound
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (1 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Chlorinated Compounds

Handling Guidelines

Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- From ChemContract?

Quality Assured

Every batch of 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-

What is 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- used for? +

2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- is a chloro-substituted intermediate widely used in nucleophilic displacement reactions used primarily in the pharmaceutical and agrochemical industries. Key applications include nucleophilic aromatic substitution (snar) for ether and amine formation and enantiopure building block for single-enantiomer drug development.

Where can I buy 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- in the USA? +

ChemContract Research is a trusted USA-based supplier of 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? +

ChemContract Research supplies 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? +

ChemContract Research supplies 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

What coupling reactions can I run with 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? +

As a chlorinated compound, 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? +

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-? +

The CAS Registry Number for 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro- is 118289-55-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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