Frequently Asked
Common questions about 2-Bromo-1-methyl-1H-indole
What is 2-Bromo-1-methyl-1H-indole used for?
2-Bromo-1-methyl-1H-indole is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics.
Where can I buy 2-Bromo-1-methyl-1H-indole in the USA?
ChemContract Research is a trusted USA-based supplier of 2-Bromo-1-methyl-1H-indole. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-Bromo-1-methyl-1H-indole?
ChemContract Research supplies 2-Bromo-1-methyl-1H-indole in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-Bromo-1-methyl-1H-indole in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-Bromo-1-methyl-1H-indole from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reactions can I run with 2-Bromo-1-methyl-1H-indole?
As a brominated compound, 2-Bromo-1-methyl-1H-indole is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
What drug discovery applications use 2-Bromo-1-methyl-1H-indole?
The Indole ring system(s) in 2-Bromo-1-methyl-1H-indole is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
How should I store 2-Bromo-1-methyl-1H-indole?
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-Bromo-1-methyl-1H-indole?
The CAS Registry Number for 2-Bromo-1-methyl-1H-indole is 89246-30-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
