Custom Chemical Synthesis & Contract Manufacturing
From milligrams to kilograms, we deliver precision organic synthesis solutions for pharmaceutical, agrochemical, and specialty chemical industries.
Comprehensive Custom Synthesis Solutions
Expert organic chemistry services tailored to your specific requirements, from route development to commercial-scale production.
Multi-Step Organic Synthesis
Complex molecule synthesis with expertise in diverse reaction types and challenging chemistry. Our PhD chemists develop efficient routes for your target compounds.
- Route development & optimization
- Heterocyclic synthesis expertise
- Chiral chemistry & resolution
- Protecting group strategies
- 5-15+ step syntheses
Process Scale-Up
Seamless transition from laboratory to commercial production while maintaining quality and optimizing cost-efficiency.
- Lab scale: mg to 100g
- Pilot scale: 100g to 10kg
- Commercial: 10kg and beyond
- Process optimization
- Safety assessments
Analytical & Quality Control
State-of-the-art analytical capabilities ensuring the highest purity and quality standards for every compound we produce.
- NMR (1H, 13C, 2D experiments)
- HPLC/UPLC analysis
- GC-MS & LC-MS
- Complete COA documentation
- Regulatory support
Custom Route Development
Innovative synthetic strategies designed for efficiency, scalability, and cost-effectiveness from concept to execution.
- Literature research
- Feasibility studies
- Alternative route evaluation
- IP-conscious design
- Cost optimization
Our Streamlined Process
A collaborative approach that ensures your project moves efficiently from initial consultation to final delivery.
Consultation
Discuss project requirements and evaluate feasibility with our expert team
Planning
Develop synthetic route with timeline and cost estimates
Development
Lab-scale synthesis to validate and optimize the route
Production
Full-scale synthesis with rigorous quality controls
Analysis
Comprehensive testing and complete documentation
Delivery
Secure packaging and ongoing technical support
Trusted Across Multiple Sectors
We provide specialized synthesis solutions to leading companies in pharmaceutical, agrochemical, and specialty chemical industries worldwide.
Pharmaceutical & Biotech
Supporting drug discovery and development with high-quality intermediates and active pharmaceutical ingredients.
- Drug intermediates synthesis
- API manufacturing
- Research compounds
- Reference standards
- Metabolite synthesis
🌾 Agrochemical
Active ingredients and intermediates for crop protection and agricultural applications.
⚡ Specialty Chemicals
Custom molecules for materials science, coatings, and advanced applications.
🔬 Research Institutions
Building blocks and specialized compounds for academic and industrial research.
Frequently Asked Questions
Find answers to the most common questions about our custom chemical synthesis and contract manufacturing services.
Project timelines vary based on complexity and scale. Simple 2-3 step syntheses can be completed in 4-6 weeks, while complex multi-step syntheses (10+ steps) may take 3-6 months. We provide detailed timelines during the feasibility study phase and maintain transparent communication throughout the project.
Typical timeframes:
- Simple synthesis (1-3 steps): 4-6 weeks
- Moderate complexity (4-7 steps): 8-12 weeks
- Complex synthesis (8-15+ steps): 3-6 months
- Scale-up projects: Add 2-4 weeks per scale transition
We're flexible with project sizes. Our minimum is typically 100mg for research compounds, but we can discuss smaller quantities for specialized projects. We scale seamlessly from milligrams to multi-kilogram production as your needs evolve.
Scale ranges we support:
- Research scale: 100mg - 10g
- Lab scale: 10g - 100g
- Pilot scale: 100g - 10kg
- Commercial scale: 10kg and beyond
Contact us to discuss your specific quantity requirements.
Yes, process development is one of our core strengths. Our team excels at developing efficient synthetic routes, optimizing existing processes, and scaling reactions from lab to production scale. We use our expertise to improve yields, reduce costs, and enhance safety.
Our process development services include:
- Literature research and feasibility studies
- Alternative route evaluation and selection
- Reaction optimization (yield, purity, cost)
- Safety and hazard assessments
- Impurity profiling and control strategies
- Scale-up protocols and technology transfer
Our FDA-registered facility follows rigorous QC protocols. Every compound undergoes comprehensive analytical testing including NMR, HPLC, GC-MS, and other techniques as appropriate. We provide complete certificates of analysis with all deliverables and maintain detailed batch records.
Our analytical capabilities include:
- NMR Spectroscopy: 1H, 13C, 2D experiments (COSY, HSQC, HMBC)
- Chromatography: HPLC/UPLC, GC, preparative HPLC
- Mass Spectrometry: GC-MS, LC-MS, high-resolution MS
- Other techniques: IR, UV-Vis, melting point, optical rotation
All compounds are delivered with complete certificates of analysis (COA) including structure confirmation, purity assessment, and full characterization data.
Absolutely. We specialize in seamless scale-up from research quantities (mg) through pilot scale (100g-10kg) to commercial production (10kg+). Our process chemists optimize each step for scalability while maintaining the quality and purity standards established at lab scale.
Our scale-up approach:
- Progressive scaling with validation at each stage
- Process parameter optimization (temperature, concentration, etc.)
- Equipment selection and safety considerations
- Cost reduction strategies without compromising quality
- Technology transfer support for your own facilities
We maintain the same team throughout your project to ensure consistency and institutional knowledge.
We provide custom synthesis services to pharmaceutical companies (drug intermediates, API synthesis), agrochemical companies (active ingredients), specialty chemical manufacturers, biotechnology firms (research compounds), and academic research institutions.
Primary industries and applications:
- Pharmaceutical: Drug intermediates, APIs, metabolites, reference standards
- Agrochemical: Active ingredients, intermediates for herbicides, pesticides, fungicides
- Specialty Chemicals: Advanced materials, electronic chemicals, specialty polymers
- Biotechnology: Building blocks, research tools, probe molecules
- Academic Research: Novel compounds, methodology development
Yes, ChemContract Research operates an FDA-registered facility with GMP certification. We maintain rigorous quality control procedures and provide complete documentation including certificates of analysis (COA) for all synthesized compounds.
Our certifications and compliance:
- FDA-registered chemical manufacturing facility
- GMP (Good Manufacturing Practice) certified laboratory
- ISO 9001:2015 quality management systems (if applicable)
- Comprehensive documentation and batch records
- Regulatory support for IND/NDA submissions
- Audit-ready facility and documentation
ChemContract Research is located in Huntington Beach, California at 9121 Atlanta Ave, Suite 800, CA 92646. Our facility is easily accessible from major Southern California locations and close to John Wayne Airport (SNA).
Contact information:
- Phone: +1 (714) 732-8549
- Email: [email protected]
- Address: 9121 Atlanta Ave, Suite 800, Huntington Beach, CA 92646
- Hours: Monday-Friday, 8:00 AM - 5:00 PM PST
We serve clients worldwide from our Southern California facility.
Our PhD chemists have extensive experience across a wide range of organic chemistry disciplines. We specialize in complex multi-step syntheses and challenging transformations.
Areas of expertise include:
- Heterocyclic chemistry: Pyridines, indoles, quinolines, benzofurans, thiophenes, etc.
- Chiral chemistry: Asymmetric synthesis, chiral resolution, chiral auxiliaries
- Organometallic chemistry: Grignard, organolithium, palladium-catalyzed reactions
- Protecting group chemistry: Complex protection/deprotection strategies
- Natural product synthesis: Total synthesis and analog preparation
- Medicinal chemistry: Drug-like molecules, SAR studies
We take confidentiality and IP protection extremely seriously. All projects begin with a Confidential Disclosure Agreement (CDA) or Non-Disclosure Agreement (NDA). Your proprietary information, structures, and processes remain strictly confidential.
Our IP protection measures:
- Standard CDAs/NDAs with all clients
- Restricted access to project information on a need-to-know basis
- Secure data storage and disposal protocols
- No publication or disclosure of client projects
- Clear ownership of IP developed during projects
- Option for custom agreements tailored to your needs
Your intellectual property is safe with us.
To provide an accurate quote, we need some basic information about your synthesis project. The more details you can provide, the more precise our estimate will be.
Information needed for quotation:
- Target molecule: Structure (SMILES, MOL file, or drawn structure)
- Quantity required: Desired amount and timeline
- Purity requirements: Minimum acceptable purity (typically ≥95%, ≥98%, etc.)
- Starting materials: Any preferred starting points or constraints
- Additional requirements: Analytical data needed, regulatory compliance, etc.
We typically provide detailed quotes within 48 hours of receiving complete information.
Yes, we understand that some projects have urgent timelines. We offer expedited synthesis services for time-sensitive projects, subject to chemistry complexity and current capacity.
Expedited service options:
- Priority scheduling for urgent projects
- Extended work hours including weekends when necessary
- Real-time project updates and communication
- Fast-track analytical testing
Contact us to discuss your timeline requirements and we'll work to accommodate your needs.
Yes, our facility is equipped to handle a wide range of challenging chemistries, including hazardous reactions, cryogenic conditions, high pressure, and air/moisture-sensitive reagents.
Capabilities include:
- Cryogenic reactions: Down to -78°C and below
- High temperature: Up to 200°C in specialized equipment
- High pressure: Hydrogenations and other pressure reactions
- Inert atmosphere: Schlenk techniques, glove box work
- Hazardous reagents: Proper handling of reactive/toxic materials
- Controlled substances: DEA-licensed for Schedule I-V compounds
All hazardous work is conducted with comprehensive safety protocols and risk assessments.
We offer flexible payment terms for established clients and can work with purchase orders, milestone payments, or custom arrangements based on project scope.
Typical payment structures:
- New clients: 50% deposit, 50% upon delivery
- Established clients: Net 30 payment terms with approved credit
- Large projects: Milestone-based payments aligned with project phases
- Accepted methods: Wire transfer, ACH, credit card, purchase orders
Contact our sales team to discuss payment terms that work for your organization.
Yes, we ship compounds worldwide. Our team handles all necessary export documentation, customs paperwork, and compliance requirements for international shipments.
International shipping services:
- Worldwide shipping with reliable carriers (FedEx, DHL, UPS)
- Proper packaging for chemical transport (UN-certified containers)
- Complete export documentation and customs support
- Material Safety Data Sheets (MSDS/SDS) in multiple languages
- Compliance with international chemical regulations
- Temperature-controlled shipping when required
We ensure your compounds arrive safely regardless of destination.







